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Faculty Details

Dr. Ashwani Sharma

Associate Professor,Chemistry & Biology


+91  (877) 250 0415

Group Webpage

Research Interests

    • Development of novel strategies utilizing nucleic acid based nanoparticles for targeted drug delivery to different cancers.
    • In vitro selection of target specific DNA/RNA aptamers using SELEX and their application in diagnostics as well as therapeutics.
    • DNA/RNA based biosensors for detection of small molecules.
    • Target-dependent nucleic acid based molecular devices.

Educational and Professional Career

  • PhD (2011): National Chemical Laboratory (NCL), Pune, Maharashtra, India
  • Postdoctoral Fellow (2011 – 2013): University of Utah, Salt Lake City, USA
  • Postdoctoral Fellow (2013 – 2015): Markey Cancer Centre, University of Kentucky, Lexington, USA
  • DST Young Scientist (2016-2017): Indian Institute of Chemical Technology (IICT), Hyderabad, India
  • Assistant Professor(January, 2017 ~): Indian Institute of Science Education and Research (IISER) Tirupati, India

Honors and Awards

  • Young Scientist (Start-up grant) from SERB, DST, Govt. of India

Selected Publications

  • Sharma, A.; Haque, F; Fengmei, P.; Shalyakhtenko, L. S.; Evers, B. M.; Guo, P. Controlled self-assembly of RNA dendrimers. Nanomedicine, 2016, 3, 835
  • Lee, T.; Yagati, A. K.; Pi, F.; Sharma, A.K. ; Choi, J.-W.; Guo, P., Construction of RNA Quantum Dot Chimera for Nanoscale Resistive Biomemory Application. ACS Nano 2015, 9, 6675.
  • Sharma, A. K. ; Plant, J. J.; Rangel, A. E.; Meek, K. N.; Anamisis, A. J.; Hollien, J.; Heemstra, J. M. Fluorescent RNA Labeling Using Self-Alkylating Ribozymes. ACS Chem. Biol. 2014, 9, 1680.
  • Sharma, A. K. ; Kent, A. D.; Heemstra, J. M. Enzyme-Linked Small-Molecule Detection using Split Aptamer Ligation. Anal. Chem. 201284, 6104.
  • Sharma, A. K. ; Heemstra, J. M. Small Molecule-Dependent Split Aptamer Ligation. J. Am. Chem. Soc. 2011, 133, 12426.


  • CHM-221: Organic Chemistry
  • CHM-314: Separation Science and Technology

Open Positions

We are constantly looking forward for applications from highly motivated young researchers. Interested candidates should directly contact by email at a.sharma@iisertirupati.ac.in