Chemistry

Research Groups  Research Facilities  Contact 

The Chemistry department at IISER-Tirupati started functioning from August 2015 with three faculty members and one technical assistant (T.A). It has since then grown progressively to the current faculty strength of nine members, from diverse research backgrounds ranging from Inorganic Chemistry & Organic chemistry to Theoretical chemistry, Chemical Biology and Material Science. It started its teaching program for the first batch of undergraduates from August 2015 with a general chemistry course followed by courses covering all the aspects in physical, inorganic and organic chemistry, well-integrated with laboratory courses. The two UG labs in the department are well equipped with all basic instruments such as fume hoods, Schlenk lines, rotary evaporators, analytical balances, PH meters etc. to conduct both modern and classical experiments.

Currently, the department has three technical assistants (T.A) and two lab assistants to assist the faculty members in the laboratory courses and to maintain the instruments. Besides, it also has a well-equipped research laboratory to accommodate 25-30 students and is being constantly upgraded with the requisite infrastructure and instruments for carrying out high quality research. Having established initial research infrastructure, the PhD program was initiated in August 2017. The department currently has 11 PhD students, and 6 post-doctoral researchers. The department is also initiating its Integrated PhD program in August 2018.

In both teaching, as well as research, the core philosophy of the department is in accordance the fact that Chemistry is the Central Science. Thus, the theory/lab courses, and the research carried out by faculty members reflect this aspect, providing the students the necessary depth in each of the core areas, and augmenting it with sufficient breadth to facilitate cutting-edge interdisciplinary research. In this regard, some specific research topics pursued in the department include: Biomolecular Chemistry of nucleic acids, peptides and lipids, Bio-Organic Chemistry and Bio-Nanotechnology, Catalysis, Asymmetric Synthesis, Synthetic Organic Chemistry, Bio-Inorganic Chemistry, Computational Organic/Inorganic Chemistry. Quantum Chemistry, Main Group Chemistry, Mass Spectrometry Applications in Chemistry and Biology, Bio-Physical Chemistry, Electrochemistry, Li-Ion Batteries and Capacitors.

To enable frontier research, the Department already has a gamut of high-end instruments including Atomic Force Microscope, IR/UV-Vis Spectrometers, Analytical HPLC, High Performance Computers, Table-top NMR etc. A 400 MHz NMR and a Mass spectrometer will soon join our list of major instruments.

Research Groups

Prolyl Polypeptides and Peptide Nucleic Acids (K N Ganesh)

Our group is interested in the studying correlation of structure with self-assembling properties of 4(R/S)-(OH/NH2)-substituted prolyl polypeptides and collagen mimetics. Another area of interest is to enhance cell permeability Peptide Nucleic Acid (PNA) through cationic and fluorinated analogues towards potential application as antisense therapeutic agents and modulate their molecular recognition features through novel Janus PNA constructs. The objective is to fundamental understanding of the connections between molecular structures, conformation and self-assembly that dictate their biological activity and morphological features important for developing materials with new properties.

Catalysis and Synthesis Group (Gopinath Purushothaman)

Our primary research focus is to develop new synthetic methods using catalysis as the main tool with special focus on visible light photoredox catalysis, transition metal catalysis & asymmetric catalysis. These synthetic methods will later be used for applications in total synthesis of natural products, drugs & other bioactive compounds.

Biomimetic Systems and Bioinorganic Chemistry group (Pankaj Kumar Koli)

Our group mainly focus on biomimetic systems and small molecule activation (O2, NO, CO, CO, and H2S, etc.) in the field of bioinorganic chemistry. In addition, we also focus on bio-sensing, catalysis and insight into the mechanistic pathways of various enzymatic reactions.

Computational and Quantum Chemistry (Raghunath O Ramabhadran)

Our group primarily works in the area of computational and quantum chemistry. We eagerly work towards new developments in application of computational tools/protocols in organic/bio-organic, inorganic, and physical chemistry. As an auxiliary area, we are also interested in scientific pedagogy.

Banerjee Research Group (Shibdas Banerjee)

We work on clinical mass spectrometry imaging for cancer diagnosis and disease biomarker discovery. Our laboratory also focuses on methodology developments using ambient ionization mass spectrometry to explore natural product discovery, microdroplet chemistry, catalysis and mechanistic organic chemistry.  

Protein Nanomechanics lab (Soumit Sankar Mandal)

The main focus of our research group is to investigate the correlation between the structure and function of multidomian proteins using Spectroscopic and Single Molecule Optical tweezers technique.

Main Group Chemistry & Catalytics (Sudipta Roy)

Our group is interested in the syntheses of carbene stabilized zero-valent heterodiatomic compounds with main group elements and/or mixed transition metal/main group elements and studying their physical and catalytic properties for the syntheses of biologically relevant small organic molecules

Energy Storage Materials (Vanchiappan Aravindan)

We perform research activity in the Materials Chemistry, specifically energy storage materials for batteries and supercapacitors. Our prime aspect of work is to realize the high energy and power capability in a single device by integrating rechargeable batteries and supercapacitors.  Recycling spent batteries and bio-waste derived material towards charge storage devices to keep our environment clean and tidy is another benchmark of our research. 

Ash Lab (Ashwani Sharma)

Ash Lab works in the area of nucleic acid aptamers, which are single stranded DNA or RNA oligonucleotides having high affinity and specificity to their target. Aptamer binding to its target is utilized in designing new biosensing platforms for disease detection and diagnostics. In addition, the lab also focuses on construction of DNA/RNA based nanoparticles decorated with aptamers and oligotherapeutics such as siRNA for the targeted drug delivery to different cancers.

 

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