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To generate ultra pure water (Type 1 water) of 18.2 MΩ.cm resistance to be used in molecular Biology applications such as PCR, sequencing and for mammalian cell culture. Type 2 water is also generated from the system used in buffer preparation. Contact: Dr. Suchi Goel
Category: Biology
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Multicolour Flow Cytometer
The BD FACS Celesta can rapidly and accurately quantify and analyze many kinds of cells, including animal cells, yeast cells, plant cells etc. Contact: Dr. Sivakumar Vallabhapurapu
Gel Imaging System Make:UVITEC, Cambridge Model: UVI Doc HD5
Gel Imaging or Gel Documentation system is used to capture digital images of electrophoresis agarose gels in order to obtain a visual record of the experimental results. Contact: Dr. Eswarayya Rami Reddy
Real-Time PCR Systems Model No: CFX Connect Thermal Cycler (96 well and 384 well plates) Make: Bio-Rad Laboratories, USA.
This Polymerase Chain Reaction (PCR) machine is used to monitor the amplification of a targeted DNA molecule during the PCR (in real time), not at its end, as in conventional PCR. Contact: Dr. Sivakumar Vallabhapurapu, Dr. Suchi Goel.
Structural and functional attributes of Microrchidia family of chromatin remodelers
Chutani, N., Singh, A. K., Kadumuri, R. V., Pakala, S. B., & Chavali, S. (2022). Structural and functional attributes of Microrchidia family of chromatin remodelers. Journal of Molecular Biology, 434(14). DOI: 10.1016/j.jmb.2022.167664
Parasite proteomics. In S. C. Parija & A. Chaudhury (Eds.),
Lodhiya, T., Devassy, D., & Mukherjee, R. (2022). Parasite proteomics. In S. C. Parija & A. Chaudhury (Eds.), Textbook of parasitic zoonoses (pp. 39-49). Series: Microbial zoonoses. Springer. DOI: 10.1007/978-981-16-7204-0_5
Immunomodulatory effect of mycobacterial outer membrane vesicles coated nanoparticles
George, E., Goswami, A., Lodhiya, T., … Mukherjee, R., & Agarwal, R. (2022). Immunomodulatory effect of mycobacterial outer membrane vesicles coated nanoparticles. Biomaterials Advances, 139. DOI: 10.1016/j.bioadv.2022.213003
Plant Signaling Group (Swarup Roy Choudhury)
We are interested in identifying the molecular and cellular mechanisms behind signal transduction in plants to unravel plant signaling pathways extending from receptors to signaling cascades and target genes that are crucial to root nodule development, plant architecture determination and stress adaptation. The important questions are: How signaling is initiated by receptor-like kinases and which… Continue reading Plant Signaling Group (Swarup Roy Choudhury)
Genomics and Systems Biology group (Sreenivas Chavali)
Our research aims at obtaining a holistic understanding of how variation in information flow affects phenotypes and fitness. We particularly focus on understanding how sequence variation- single nucleotide changes, repeats or compositional bias within intrinsically disordered proteins/regions influence the function(s), regulation and evolution of biomolecules, with special emphasis on health and disease. To address this,… Continue reading Genomics and Systems Biology group (Sreenivas Chavali)
Single Molecule Biophysics Lab (Nibedita)
Our research focuses on amalgamating DNA nanotechnology and biomolecule in its native form to answer basic questions that are pertinent to the field of Biophysics. In particular we are interested in designing reconfigurable DNA structures responsive to external stimuli and its potential application in therapeutics. We are also interested in exploring the mechanism of biomolecule… Continue reading Single Molecule Biophysics Lab (Nibedita)