Faculty Details

Research Interests

NF-kB and MAPK Signaling, Inflammation, Immunity and Cancer

Educational and Professional Career

• Ph.D (04, 2004):  Forschungszentrum, University of Karlsruhe, Karlsruhe, Germany
• Postdoctoral Fellow (05, 2004 – 2005): Leibniz Institute on Ageing, Fritz Lipmann Institute, Jena, Germany
• Postdoctoral Fellow (11, 2005 ? 08, 2009 ): University of California, San Diego, USA
• Faculty, Research Associate (09, 2009 – 12, 2009): University of Cincinnati, USA
• Tenure ? Track Assistant Professor (2010 – 2013): University of Cincinnati, Cincinnati, USA
• Faculty (2014): Louisiana State University Health Science Center, Shreveport, USA
• Associate Professor:(Current Position) Indian Institute of Science Education and Research, Tirupati, India

Honors and Awards

• DST ?SERB ECR Award, SERB, New Delhi

Selected Publications

• Transcriptional repression by the HDAC4-RelB-p52 complex is essential for Multiple Myeloma survival and growth Subrahmanya D Vallabhapurapu1, Sunil K Noothi1, Derek Pullum1, Charles H Lawrie2, Rachel Pallapati1, Veena Potluri1, Christian Kuntzen3, Sohaib Khan1, David R Plas1, Robert Orlowski54 Marta Chesi5, W. Michael Kuehl6, P. Leif Bergsagel5, Michael Karin7 and Sivakumar Vallabhapurapu1*. *Corresponding Author (Citations: 11) Nature Communications 2015 Oct 12;6:8428. doi: 10.1038/ncomms9428 ” , Nat Commun. 4, 12;6:8428 (2015).
• Transcriptional Repression of Bim by a novel YY1-RelA complex is essential for the survival and growth of Multiple Myeloma Veena Potluri1E, Sunil K Noothi1E, Subrahmanya D Vallabhapurapu1E, Sang-Oh Yoon1, James J Driscoll2, Charles H Lawrie3 and Sivakumar Vallabhapurapu1* PLoS One. 2013 Jul 10;8(7):e66121 *Corresponding Author Citations: (8) “, Plos One 3, . 2013 Jul 10;8(7):.
• Non-redundant and complementary functions of adaptor proitsmine teins TRAF2 and TRAF3 in a ubiquitination cascade that regulates NIK-dependent alternative NF-kB pathway Sivakumar Vallabhapurapu, Atsushi Matsuzawa, Weizhou Zhang, Ping-Hui Tseng, Jonathan J Keats, Haopeng Wang, Dario AA Vignali, Lief P Bergsagel and Michael Karin Nature Immunology 2008 Dec;9(12):1364-70 (Citations: 447) ” “, Nature Immunology 73, 2008 Dec;9(12):1364-70 .
• Regulation of NF-kB transcriptions factors in the immune system. Sivakumar Vallabhapurapu and Michael Karin Annual Review of Immunology 2009;27:693-733. (citations: 1612) ” “, Annual Review of Immunnology 30, 693 (2009).
• Essential cytoplasmic traslocation of a cytokine receptor-assembled signaling complex Atsushi Matsuzawa*, Ping-Hui Tseng*, Sivakumar Vallabhapurapu, Jun Li Luo, Zhang W, Wang H, Dario AA Vignali, Gallagher Ewen and Michael Karin Science, 2008 Aug 1; 321 (5889): 663-8 (Citations: 193) “, Science 29, 663 (2008).

Teaching

• BIO 121 Introductory Biology II: Cellular and Molecular Biology
• BIO 122 Biology Lab: Biochemistry and Molecular Biology
• BIO 323 Advanced Immunology

Open Positions

An position for a JRF is expected to be available soon in my lab.