IISER Tirupati is having a well-established hostel. The building has 4 floors. Each floor has 46 rooms (in total 184). All rooms are equipped with furniture (i,e cot, mattress,study tables, chairs, pedestals, and almirahs). Drinking water and washing machine facilities are provided on each floor. All bathrooms are connected with hot water facility for bathing purpose. In the ground floor, we have a Gym, a room for music practice and indoor games, well-furnished study room, a TV Hall, a wellness clinic, a modern kitchen and a spacious dining hall.

Additionally, there is also 24x7 security services separately for Girls and Boys to take care of the students in addition to Hostel Managers.